Most agree that clozapine levels provide the most value while others suggest norclozapine levels should also be considered. Clozapine page 14 therapeutic dose range of clozapine usual dosage range is 200 450 mg day divided dose. Clozapine is a substrate for many cytochrome p450 isozymes in particular cyp1a2 cyp2d6 and cyp3a4.
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